Data on the negative effects of the common plasticizer phthalates keeps on coming. Last month, it was the relationship between phthalates, insulin-resistance and male waist circumference and this month it is the effect of this toxin on thyroid function in men. The journal Environmental Health Perspectives has published numerous articles on the subject but the last two issues seem to really bring home the fact that we need to look at phthalates more closely and avoid exposure as much as possible.
The June 2007 article, authored by Stahlhut, et al, shows a link between levels of urinary excretion of phthalates and insulin resistance as well as obesity in males. The gist of the article found here, is that phthalates may be anti-androgenic, meaning it blocks the production of testosterone. We know that by depressing testosterone you see an increase in cholesterol and a decrease in the ability to regulate blood sugar.
This month, researchers Meeker, Calafat and Hauser report on a study they did which looked at 408 men and measured their urine output of two forms of phthalates. There conclusion was that there may be an association between phthalate concentrations and altered free T4 and/or total T3 levels. This is the first time that human studies were conducted on this relationship and it seems to back up the limited animal research that showed this same correlation.
To find out where your levels are, have your doctor call Lab Interpretation LLC at 775-851-3336 and ask about the Environmental Pollutants Panel and you can check not only your phthalate level, but a number of other petrochemical solvents (benzene, toluene, xylene, parabens, trimethylbenzene and styrene), Phthalates are commonly found in drinking water as well as cosmetics, shampoos, perfumes and other skin and hair care products. Go to the Environmental Working Groups website (click the link) and go to their Skin Deep database. There you will find out where your exposures may be from.