In an article from Discover Magazine, Ben Harder reports on an important study published in PLoS Medicine by Irving Kirsch, et al that basically says that antidepressant drugs pretty much don’t work any better than placebo. This is just another in a series of papers that suggest that you try other alternative methods like Omega 3 fatty acids, amino acid and nutrient therapies before you try meds.
My suggestion would be to run a plasma amino acid test before even thinking about antidepressant medications and see if a customized amino acid supplement might help. Far fewer side-effects and a lot of positive effects on energy and general well-being might just happen.